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Sp could also increase the efficacy of L-DOPA, extensively used in palliative care of PD patients, by subsidence of its long term toxicity

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High sodium-induced oxidative stress and poor anticrystallization defense aggravate calcium oxalate crystal formation in rat hyperoxaluric kidneys

In a recent work published on August 2023 employing HO-1 knock-out mice, the administration of simvastatin along with angiotensin II provoked renal injury due to accelerated rabdomyolysis [236]