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summarized and analyzed clinical data on specific antibody-active substance conjugates that can cross the BBB [191]

Mouse primary epidermis was isolated from 12 day old wild type and C/EBP knockout B6N:129 hybrid mouse skin by flotation in Hanks Balanced Salt Solution (H9394, Sigma-Aldrich) and 0.25% trypsin (15090-046, Life Technologies) (Sterneck et al., 1997

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