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Description
Interestingly, the metabolic dysregulation induced by an HFD manifests multifaceted pathogenic effects

Therefore, patients should be advised to avoid exposing the application site to sources of direct heat, such as heating pads or electric blankets, heat lamps, saunas, hot tubs, heated water beds, and prolonged direct sunlight

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doi: 10.1097/MD.0000000000000857
