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Description
An imbalance between MG production and Glo1 activity can lead to MG accumulation, which has been implicated in renal injury
2023 min, 95%B
Prez PS, Romaniuk MA, Duette GA, Zhao Z, Huang Y, Martin-Jaular L, et al
M1 microglia are more resistant to ferroptosis than M2 microglia since they have less IRP activity and cellular labile iron pool, and higher ferritin levels, which help maintain neuroinflammation, perpetuate iron dysregulation, and ferroptosis-mediated neuronal death [298, 310, 312]
