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Adding to this tension, recent negative clinical trials of iron chelators in degenerative diseases where ferroptosis has been implicated have tempered enthusiasm for iron-focused strategies and prompted a re-evaluation of irons true role in these diseases, and by extension, ferroptosis
10.1038/s41589-020-00728-9 8 AndrusP
doi: 10.1089/ars.2009.2697
In healthy adult subjects, single subcutaneous doses of CJC1295 led to a 2 to 10fold rise in GH for six days or more and a 1.5 to 3fold increase in IGF1 that persisted for 911 days
