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In addition, increased permeability likely promotes the low-grade chronic inflammation, termed inflammageing [72][67][75], and many studies link low grade inflammation with bone loss [84][85][62]
Epithelialmesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI
Histone acetylation enzymes coordinate metabolism and gene expression
Senescence and the SASP: many therapeutic avenues
