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The lipotropic agents (methionine, inositol, choline) are pH-sensitive and oxidise rapidly once exposed to air and moisture, which is why the 72-hour window exists rather than the 28-day stability window you'd see with straight methylcobalamin

For instance, cramps may occur during or after intense physical activity, such as running or exercising for an extended period

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The peptide also appears to influence neurotransmitter systems, particularly the dopaminergic and GABAergic pathways, which may contribute to its observed effects on neurological function and behavior