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Decreasing oxylipin diol levels by DMSO could be used as a treatment complementary to sEHI: while inhibition of sEH would help prevent the formation of new diols, DMSO would eliminate pre-existing diols that may have accumulated prior to sEHI treatment (Figure 5)

2.2 Abnormal amino acid antioxidant system System Xc , GSH, and GPX4 constitute a critical signaling axis in the regulation of intracellular lipid peroxidation and ferroptosis (Yu et al., 2025)

Documented buccal protocols: Buccal strips offer a practical middle ground: bioavailability meaningfully higher than oral capsules, without requiring injection

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