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Inconsistent results, however, were also found among studies of the same cancer

Upon binding with specific death ligands, death receptors receive extracellular death signals and initiate apoptotic signaling by recruiting specific adaptor proteins, which subsequently activate the caspase cascade

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They then recruit procaspase-1 and apoptosis-associated speck-like proteins containing CARD (ASC) to form inflammasomes [104,105,106]
