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Moreover, many studies showed that metformin improves the expression of BDNF by increasing the histone acetylation along with the BDNF promoter, which was attributed to the activation of AMPK and CREB (Ameen et al., 2022
[DOI] [PubMed] [Google Scholar] 95.Wang Y., Tao A., Vaeth M., Feske S
Jun B.-H
