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This trend is also noticeable when comparing the panels in Supplemental Figure 2 as well as between Figure 9 and Supplemental Figures 35, where most of the original clusters shown in blue remain constant throughout the 4 figures, while the ones that become significant are depicted mainly as red or purple, reflecting a shift from hypometabolism of significant metabolites toward hypermetabolism for newly significantly different metabolites

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Antioxidant effect of acetyl-L-carnitine against cisplatin-induced cardiotoxicity