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Description
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
Alleviation of the macrophage cholesterol burden is critical to the inhibition of plaque progression as excess membrane FC promotes inflammatory signaling and cell death (Discussed later)
The human evidence is limited, but the mechanistic rationale is enough that this remains an active research area
[DOI] [PubMed] [Google Scholar] Fenves A
