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The scalp's collagen matrix provides structural support to follicles

In addition, a specific miRNA may exert multiple regulatory effects by binding to several targets of metabolic signaling pathways, illustrated by the example of let-7 that binds to 3UTR regions of INSR, IRS-2, and IGF-1R and regulates their expression (95)

Circulation 106:939944 Kadri Z, Lefevre C, Goupille O et al (2015) Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis

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