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As Kannt & Pfenninger highlight in Frontiers in Physiology , maintaining NAD levels is a cornerstone of metabolic health, supporting mitochondrial function and improving resistance to metabolic stress (Kannt & Pfenninger, Frontiers in Physiology )

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As an insight, there is a study of innate vascular failure caused by application of neuroleptics, amphetamine, and domperidone that rapidly induced severe occlusion/occlusion-like syndromes in rats and stable gastric pentadecapeptide BPC 157 as therapy [142] (Figure 3)

Some doctors are starting to listen: In one Swiss study (2), almost half of all general practitioners agreed with prescribing B12 for unexplained fatigue