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In addition to contributing to the detoxification of MGO, DJ-1 has been proposed to metabolize MGO and glyoxal (a byproduct from fatty acid peroxidation) to generate D-lactate and glycolate, respectively, and that these metabolites contribute to the maintenance of mitochondrial function [316]

To date, there have not been any significantly well established clinical studies, to determine or verify the results of BPC-157 as a therapeutic treatment for wound healing

[DOI] [PMC free article] [PubMed] [Google Scholar] 223.Regazzoni L, de Courten B, Garzon D, Altomare A, Marinello C, Jakubova M, Vallova S, Krumpolec P, Carini M, Ukropec J, Ukropcova B and Aldini G

human studies report only mild, transient side effects (occasional headache or nausea)