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Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts

Microglial UCP2 mediates inflammation and obesity induced by high-fat feeding

Although intrastrand DNA crosslinks represent approximately 95% of all DNA lesions, ICLs are more cytotoxic

There are three radical reactions mainly initiated by superoxide Figure 1 (i) under the influence of superoxide dismutase (SOD), the superoxide is converted into hydrogen peroxide (H 2 O 2 ), which is subsequently converted to water and molecular oxygen by GSH peroxidase (GPx) or catalase