nac vs glutathione supplementation comparison Vitamin D, Glutathione, and NAC: Important Relationships to Pay Attention To The Combined Antioxidant Effects of

Given that core metabolic processes, including nucleotide synthesis, glycolysis, and redox defense, are fundamentally shared with normal proliferative tissues, broad-spectrum metabolic inhibition often lacks true selectivity and precipitates dose-limiting systemic toxicities [43]

Potential risks include unpredictable pharmacokinetic interactions, immunogenicity, injection site reactions, gastrointestinal adverse effects, and disruption of copper homeostasis

Cell 147 , 840852 (2011)

Busulfan is an anticancer drug that kills undeveloped germ cells, affects spermatozoal production, and induces male infertility, and the drug has been used to establish a model of oligospermia