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Description
Deferasirox alleviates dss-induced ulcerative colitis in mice by inhibiting ferroptosis and improving intestinal microbiota
TNF-, tumour necrosis factor-alpha
This process increases IL-1 and turns macrophages into pro-inflammatory M1 type, which aggravates immune dysregulation by disrupting T lymphocyte balance (Zhou et al., 2022)
Li LX, Fan LX, Zhou JX, Grantham JJ, Calvet JP, Sage J
