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Changes to this system can have serious consequences: A weakening of the AMOC could cause regional cooling in the North Atlantic and Europe

As summarized by Sharpe and Killcross [186], lesions of IL prevent appetitive instrumental responding becoming habit-like and insensitive to alterations in the valuation of the goal, following over-training [187], and inactivation re-instates goal directed sensitivity of over-trained instrumental responses [188]