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Hopkins CR, Lindsley CW, Niswender CM (2009) mGluR4-positive allosteric modulation as potential treatment for Parkinsons disease

--- The Clinical Frontier The strongest human evidence now supports: Metformin (metabolic reprogramming) NAD boosters (mitochondrial repair) MSC infusions & TPE (cellular rejuvenation) GLP-1 agonists (metabolic efficiency) The future lies in combination strategies integrating metabolism, cellular repair, and mitochondrial support for multimodal rejuvenation

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It is also vital for immune function, helping to fight infections and diseases