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Eaton DM, Livingston JH, Seetharam B, Puntis JW
The best studied plant-derived phytotoxic 1,4-NQs are plumbagin and juglone, which induce ROS production in tobacco BY-2 cells, ultimately resulting in programmed cell death
In contrast, an excess of dopamine to the prefrontal cortex and striatum from mesolimbic dopamine pathways induces hyperstimulation of D2receptor neurons, responsible for the positive symptoms [5]
doi: 10.1002/gps.1856
