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The Impact of Free Radicals on Canine Health Free radicals are a natural byproduct of cellular metabolism, but they can also be introduced into the body through environmental factors such as pollution, radiation, and certain chemicals

However, in the presence of oxidative or nitrosative stress, GST can form homodimers that alter the reduced states of cysteine residues in its structure, resulting in JNK dissociation from the GSTJNK heterocomplex and causing subsequent activation of the c-Jun protein

With enough B vitamins (B6, B9, B12), Hcy either turns back into methionine or becomes cysteine