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Description
doi: 10.1128/JVI.80.1.138-148.2006
Proc Natl Acad Sci U S A, 1970
Nature 457, 313317
Animal Model:Sprague-Dawley rats (325-375 g) [6] Dosage:0.32 g Administration:Intrathecal injection (i.t.), single dose Result:Caused a significant allodynia 3 hours post injection, which was blocked by coadministered LPS-RS (Lipid A from Rhodobacter sphaeroides, a type of lipopolysaccharide (LPS) that acts as an antagonist to Toll-like receptor 4 (TLR4))
