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2.4 Correlation between GPX4 downregulation and OA severity Extensive clinical pathological analyses and rigorously controlled animal model studies collectively reveal a clear pattern: the protein expression level or biological activity of GPX4 typically shows a significant negative correlation with the severity of OA lesions

Brain and Nervous System Dysfunction and Damage High Hcy levels interfere with SAMe and DNA methylation, affecting brain function

doi: 10.3390/cells10102655 181 NagyGKonczAPerlA

[DOI] [PubMed] [Google Scholar] (105).Kwon BG
