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Description
Data-driven adjustments are key

Firstly the Review was based on research papers that were very suspect and involved groups of individuals that did not represent a wide cross section of society (the primary study was of mainly elderly males)
Make one change at a time when troubleshooting

Interestingly, while NMN is known to be beneficial for aging-associated declines, this data suggests that NMN might have a neurotoxic effect in cases of axonal degeneration 54
