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Description
Inhibition of TrxR leads to increased ROS levels in cancer cells to a lethal level, consequently leading to activation of cell death mechanisms
Circulation 125 (11), 13561366
Comprehensive protocols built around individual lab work and goals
In the short term, UPR acts as an adaptive response that enhances the cells ability to manage ERS by restoring ER homeostasis through protein processing, thereby promoting cell survival
