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It is primarily used for obesity treatment and is currently in Phase III clinical trials
Khaledian S, Dayani M, Fatahian A, Fatahian R, Martinez F
The H3 receptors are acting as a feedback loop to restrict histamine and other neurotransmitter release in certain brain regions.[ref] The study also linked histaminergic neuron expression and changes in the brain to ADHD and major depressive disorder
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