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Description
Unfortunately, Current DNA methylation inhibitors tend to trigger hypomethylation, exacerbating genomic instability [91]

She was careful to explain exactly what they were and what they weren't

The rationale was the dehydrogenation activity was only an unusual means to provide the trans -2-decenoyl-ACP for isomerization to the essential cis -3-decenoyl-ACP

The resulting macromolecular damage promotes the activation of a wide range of DNA damage repair pathways, including nucleotide excision repair (NER), base excision repair (BER), homologous recombination (HR), and ATR/ATM cell cycle checkpoints (51)
