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The brain is metabolically expensive neurons consume a disproportionate share of the body's ATP

Restoring Brain Function via Low-Dose THC: Preclinical studies suggest very low-dose THC can reverse age-related declines in cognitive performance by acting on the endocannabinoid system

Considering that (1) MDD is a chronic stress condition with reduced HRV [29], and reduced autonomic responses to acute stress [5] and (2) taVNS can selectively activate vagal afferents and modulate the central autonomic network, we hypothesized that taVNS would increase acute stress reactivity, restore blunted HRV, and reduce inflammatory response to acute stress in participants with MDD and healthy controls

Deal, Jeremy Schmutz, Jane Grimwood, Hume Stroud, Steven E