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Journal of Pediatric Hematology/oncology 44 (3): e677e681

Signs Your B12 Levels May Need Monitoring Key warning signs include tingling or numbness in the extremities, persistent fatigue, breathlessness, glossitis, and mood changes

The 6 patients receiving TB4 experienced a 35.1% decrease in eye discomfort and a 59.1% reduction in total corneal fluorescein staining, relative to the control group [35]

And finally, as pointed out later in the 1980s [295], Selyes stress (general adaptation syndrome, derangement of which for many stress-induced diseases) has been largely discharged, and replaced by new, humbler ideas, but more precise in nature [295]