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Nonetheless, labeling patterns for multiple TCA cycle intermediates (including aspartate, malate, fumarate, citrate, and -ketoglutarate) mirrored those observed in the MEC-1/N M cells, with higher glutamine-derived incorporation in CLL/N M compared to CLL/N WT (Supplementary Fig
Interestingly, compared with sedentary controls, bone marrow-derived macrophages (BMDMs) from exercise-trained mice show reduced LPS-induced NF-B activation and proinflammatory gene expression, along with increased expression of M2-related genes, these changes are associated with improved mitochondrial quality, increased reliance on oxidative phosphorylation, and reduced ROS production (35, 36)
Cui Q., Fu S., Li Z
Di Martino MT, Riillo C, Scionti F, Grillone K, Poler N, Caracciolo D, et al
