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Any appetite-related changes are secondary: as sleep improves, energy returns, and body composition shifts, patients naturally feel more motivated to support those changes with better nutrition

The result is greater than what any single peptide could deliver in isolation

This article summarizes current progress in understanding the machinery of Exos biogenesis

These include moving beyond single biomarkers to adopt multidimensional assessments that combine biomarkers, neuroimaging, digital phenotyping, and behavioral measures [580, 582, 610, 638]
