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Secondline topical agents, opioids, and BoNTA offer alternatives

Treatment with B 12 injections is efficacious in restoring normal metabolism, alleviating symptoms, and reversing haematological and some neurological complications of deficiency.23 Anaemia usually resolves within six to eight weeks, but coexisting iron deficiency may be present and need oral iron supplementation7 and, in severe cases, parenteral iron infusion

W., Li W., Francis G

In MVA pathway, IPP and COQ10 are two important products of this pathway 14
