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For now, indirect metabolic biomarkers remain the primary feedback mechanism
[DOI] [PMC free article] [PubMed] [Google Scholar] Kaarniranta K, Uusitalo H, Blasiak J, Felszeghy S, Kannan R, Kauppinen A, et al
For absorption-related deficiency (pernicious anaemia, post-bariatric surgery, Crohns disease) injections are necessary because the gut cannot absorb oral B12 regardless of dose
Additionally, older adults who naturally have a more challenging time absorbing vitamin B12 or those on certain medications that affect B12 absorption may be ideal candidates
