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However, as the GLP-1 albumin fusion and unfused albumin have the same theoretical pI, and only small differences in pH-dependent net charge, this probably does not explain the discrepancy between their FcRn binding properties and cellular handling or plasma half-life

Milder JB, Liang LP, Patel M

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Comparison of the metabolic profiles in the plasma and urine samples between autistic and typically developing boys: a preliminary study