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For instance, ROS can activate AMPK, inhibit the mammalian target of rapamycin (mTOR), and promote catabolic processes under stress conditions [547, 548]
In severe cases, this can progress to acute liver failure
Evaluation of Electrophysiological Effects of Melatonin and Alpha Lipoic Acid in Rats with Streptozotocine Induced Diabetic Neuropathy
Targeted enhancement of GPX4 activity or restoration of GSH synthesis capacity can effectively reduce neuronal ferroptosis in the brains of AD model animals and improve cognitive dysfunction, suggesting that this axis is a potential therapeutic target for AD
