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Conversely, since the LDH isoform derived from the LDHB gene is primarily responsible for the oxidation of lactate to pyruvate the high level of LDHB expression in -cells ensures that the bulk of lactate generated from pyruvate via the actions of LDHA derived LDH is rapidly oxidized back to pyruvate

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Conclusions Ferroptosis represents a compelling molecular pathway that unites iron dyshomeostasis and oxidative stress with neuronal loss in neurodegenerative diseases

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Front Immunol (2022) 13:972503

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The degradation of a nonapeptide, sleep-inducing-peptide, in rat brain: comparison with enkephalin breakdown

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