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Carnitine can effectively inhibit mitochondria-dependent apoptosis by regulating the balance of Bcl-2/Bax, inhibiting the mitochondrial permeability transition (MPT), and reducing mitochondrial membrane damage and the release of apoptosis-related factors [14, 15]

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McKennas laboratory was supported in part by NIH Grants 5P01 HD016596 and P01 HD085928

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L.ChengC

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Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

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