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In this perspective, the reaction catalyzed by pyruvate carboxylase plays an anaplerotic function, catalyzing the formation of oxaloacetate
Another study, also investigating the relationship between Toxoplasma infection and cognitive impairment in nonpsychiatric controls, bipolar subjects, and patients with schizophrenia, reported a significant association between the anti- Toxoplasma IgM (but not IgG) levels and cognitive impairment in the nonpsychiatric controls in RBANS total score, immediate memory, language, and visuospatial/constructional ability
No multi-year human studies exist to characterize cumulative adverse events beyond that window
