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All of the residues were mutated to alanine (except for A295F and V296F) because it displays no polar character and less steric hindrance

Statements Data availability statement The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding authors

In this diabetic wound healing model, they use a high-sugar + high-fat diet, plus a toxin (streptozocin) that damages pancreatic beta cells
