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Mitochondrial dysfunction and oxidative stress in bone marrow stromal cells induced by daunorubicin leads to DNA damage in hematopoietic cells
Despite compensatory upregulation of sodium-dependent citrate transporters (NaCitT) in advanced tumors, accelerated citrate consumption consistently outpaces extracellular uptake (75)

High GLS expression in colorectal cancer has been demonstrated to result in reduced T-cell infiltration and toxicity, which is a significant factor contributing to the poor prognosis observed in patients with this condition

This research not only confirmed the therapeutic potential of RT2 as a novel anticancer agent but also revealed its molecular mechanism of inhibiting tumor growth through the precise regulation of protein expression networks (Maijaroen et al., 2022)
