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Description
Bepirovirsen, developed by GlaxoSmithKline (GSK), is a 2-MOE-modified ASO that targets all HBV RNAs, promoting RNase H-mediated RNA degradation, reducing HBV replication, and inhibiting HBsAg production
This research work has been designed to estimate the EST and CZP in marketed formulation with BBD approach for the optimization of chromatographic conditions in HPLC method development and validated method as per International Council for Harmonization (ICH) guidelines
doi: 10.3390/ijms24032576
Nature 345 , 458460 (1990)
