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Notably, the UniProtKB entry for C16orf87 (UniProtKB Q6PH81) annotates a putative coiled-coil region between residues 104132

However, it's important to contextualize this assessment within the limitations of the available evidence: most safety data comes from relatively small studies, often of short-to-moderate duration, conducted primarily in the Soviet Union, Russia, and Eastern Europe where methodological standards and reporting practices have sometimes differed from Western pharmaceutical trial requirements

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