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doi: 10.1110/ps.0243403
Gene environment interactions and predictors of colorectal cancer in family-based, multi-ethnic groups

Following the use of SAM in methyl transfer reactions, the resultant S-adenosylhomocysteine (SAH or AdoHcy) is hydrolyzed by adenosylhomocyteinase (also called S-adenosylhomocysteine hydrolase) to yield homocysteine and adenosine

TMZ (Sigma-Aldrich) was dissolved in DMSO and added to cells at a final concentration of 100 M as previously described ( PGLS Expression and Activity PGLS expression in tissue samples was assessed by quantitative RT-PCR using a SYBR Green assay kit with the following primers: forward primer (TGTGGCAACTGGAGAAGGCAAG), reverse primer (CTCGTCCAAGAACCAGCACAGT)
