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Description
[] The liver includes ~60%80% of hepatocytes and ~20%40% of nonhepatocytes

An additional insult or pathogenic factor, often referred to in the literature as the second hit, is required to trigger the progression from simple steatosis to steatohepatitis (MASH), characterized by hepatocellular injury, inflammation, and varying degrees of fibrosis [32]

Lambeir A

The transition metal (Fe 3+ , Cu 2+ , and Zn 2+ ) concentration increases due to the disequilibrium in homeostasis, which regulates the oxygen stress
