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reliable data could not be obtained at 5-amino-1MQ concentrations above 100 M due to inference with the NAMPT assay readout signal (Figure 4D, Table 3)

Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017

A recent review of positron emission tomography (PET) studies with opioid receptor-specific tracers posit a central role of the opioid system for positive affective states (Nummenmaa & Tuominen, 2017)

2016 Oct 12;9:4771