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This distinction matters not because B12 injections are inherently dangerous, but because the systems surrounding the injection determine how quickly and effectively a provider can respond if something unexpected occurs

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It should be emphasized that the principle of peptide regulation of gene expression can either consist in direct binding of short peptides to DNA or be mediated by interaction with effector molecules (transcription factors and DNA/RNA-binding proteins, including zinc finger proteins and ncRNA)

This is important not only because GLP-1 receptor agonists have become very popular as pharmaceutical drugs to treat diabetes and obesity (JY Wang et al.), but also because, as we will see later, GLP-1 prevents amyloidosis of the amyloidogenic small peptide hormone amylin, which is normally released along with insulin from the pancreatic -cells when blood sugar levels are elevated