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869 One hypothesis is that these residues play multiple roles, one of which is to initiate ligand exchange with the metallochaperone

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Further subgroup analyses showed that patients who had undergone radiotherapy or concurrent chemoradiotherapy also exhibited lower DRS values and worse survival outcomes, implying that such pretreated patients may be particularly responsive to sermorelin [1] Finally, univariate and multivariate Cox regression analyses were performed to determine whether DRS was an independent prognostic factor