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FRDA patients exhibit decreased blood plasma-iron levels and cytosolic ferritin levels shifted to higher concentration of its light-chain than heavy-chain counterparts in the dentate nucleus, indicating iron transport from the circulation but bypass of cytosolic storage (Koeppen et al., 2007

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Bayley EM, Ivy ML, Shewale JB, Ge PS, Antonoff MB, Francis AM, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC , Roth JA, Sepesi B, Vaporciyan AA, Walsh GL, Lee JJ, Louie BE, Swisher SG

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