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Notably, individuals with more advanced liver disease exhibited the highest endogenous BAC, and BAC could be manipulated to increase or decrease by pre-treating patients with an infusion of an inhibitor of hepatic alcohol metabolism (4-methylpyrazole) or with a course of broad-spectrum antibiotics, respectively (63)
Imiquimod was well-tolerated with no life-threatening (grade 4) toxicity
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This effect proves particularly valuable for tendon and ligament injuries where cell infiltration typically occurs slowly
